Verona Pharma has reported that the its novel anti-asthmatic compound, RPL554, is entering a second 28-day experimental inhalation toxicology study in another species in order to demonstrate safety, before moving onto the proof of concept clinical trials early 2008.
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RPL554 is a long-acting bronchodilator or anti-inflammatory molecule being developed to treat hay fever (rhinitis), asthma and chronic obstructive pulmonary disease.
The inhalation studies will be undertaken by Lab Research of Hungary, which is already conducting other safety studies on RPL554.
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