Hydra Biosciences, Cubist Form Collaboration

Hydra Biosciences has entered into an agreement with Cubist Pharmaceuticals for a joint collaboration to develop novel ion channel drugs. The deal focuses on Hydra’s research and development program for ion channel compounds that target the TRPA1 receptor.

Under the terms of the agreement, Hydra receives an upfront payment of $5m from Cubist. The agreement allows for Cubist to support Hydra’s internal development on the TRPA1 program by providing $5m in research and development funding per year for two years, with an option to renew.

The joint development program will build on the existing R&D base of Hydra’s TRPA1 compounds, preclinical data, and pharmacology studies. As the collaboration progresses into potential future stages, Hydra is eligible for potential development milestones and royalties on products produced from the joint program. The goal of the program is to identify TRPA1 drug candidates for use as acute care therapeutics for the management of pain.

Steven Gilman, chief scientific officer of Cubist Pharmaceuticals, said: “As we continue to build an acute care pipeline, we are excited to develop a partnership with Hydra that provides us access to a novel platform for developing acute care therapeutics for the management of pain.”

Russell Herndon, chief executive officer of Hydra Biosciences, said: “We are pleased to collaborate with Cubist and to advance innovative drug candidates using our ion channel platform. While our platform has potentially broad applications in the treatment of pain, inflammation, cardiovascular and other diseases, this collaboration is a step forward in advancing our pipeline for novel ion channel drugs for pain management.”