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Novartis, Wellcome Trust To Develop Vaccine For Typhoid Fever

E5.15 million granted to fund preclinical development and phase I and II clinicla trial studies for the vaccine

Novartis has announced that the Novartis Vaccines Institute for Global Health has been awarded a grant from the Wellcome Trust to develop a bivalent vaccine for typhoid fever.

The E5.15 million grant will fund preclinical development and phase I and II studies for a vaccine that protects against both S. Typhi and S. Paratyphi A. The currently available vaccines for S. Typhi do not protect infants and young children. S. Paratyphi A is a growing problem causing 25-50% of all typhoid cases.

Dr. Daniel Vasella, Chairman and CEO of Novartis, said: The bivalent vaccine being developed by NVGH will use a novel approach to increase efficacy and address the needs of patients that other vaccines have not. This will ultimately have the potential to eradicate this disease.