NIH and partners commence HIV vaccine efficacy trial
The new Phase 2b proof-of-concept study, called Imbokodo, aims to enroll 2,600 HIV-negative women in sub-Saharan Africa. Of 1.8 million new HIV infections worldwide in 2016, 43 percent
Electra Therapeutics has received orphan drug designation (ODD) from the US Food and Drug Administration (FDA) for ELA026, an antibody therapy to treat hemophagocytic lymphohistiocytosis (HLH).
This includes three marketed products: recently approved and launched Vabomere (vaborbactam/meropenem), and established commercial products Orbactiv (oritavancin) and Minocin IV (minocycline). The acquisition was unanimously approved by Melinta’s
Erenumab delivered clinically meaningful and statistically significant differences from placebo for all primary and secondary endpoints in the study, dubbed Strive. Erenumab functions by targeting and inhibiting the Calcitonin Gene-Related Peptide
The trial showed statistically significant and dose dependent increases in lean body mass and less head following treatment with VK5211 compared against placebo. In addition, the study also reached secondary endpoints,