Reaction Biology gets NIH grant for bromodomain research
The grant will help fund an examination of the interaction of over 1400 FDA-Approved drugs and drug-like compounds with a variety of bromodomains, and facilitate the creation of
Tolerance Bio has signed an agreement securing an exclusive licence from Tanabe Pharma for TLB-33, a clinical-stage anti-IL-33 monoclonal antibody, in a deal that includes potential development and sales milestone payments of up to around $560m.
This patent, with a priority date of 2008, covers screening mechanisms for identification of small molecules that can modulate the function of a nuclear receptor target that was
After the respective agreement, both Proteus and Boston Children’s Hospital will remain as key members of the collaboration steering committee. The agreement includes about $85m in upfront and
The results showed patients with relapsed/refractory CLL taking venetoclax in combination with rituximab, had an overall response rate (ORR) of 84%. In addition, six patients stopped venetoclax after