PerkinElmer, a provider of technology, services and solutions to the diagnostics, research, environmental, safety and security, industrial and laboratory services and Abbott will jointly present on the applications of exact mass Time-of-Flight (TOF) mass spectrometry for advancing pathogen detection research at the American Society for Mass Spectrometry (ASMS) conference in Salt Lake City.
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PerkinElmer and Abbott’s presentation will be based on their work together incorporating PerkinElmer’s exact mass TOF technology as part of Abbott’s Plex-ID detection platform, employed in pathogen detection research.
According to PerkinElmer, currently intended for research and non-diagnostic use only, Plex-ID is the only high-throughput technology that offers rapid and broad identification, detailed genotyping, and characterization and recognition of emerging organisms.
The Plex-ID system employs a combination of molecular technologies, including polymerase chain reaction (PCR) for gene amplification and exact mass TOF analysis to rapidly characterize known and unknown organisms. It is designed to address a significant unmet need by providing test results in six to seven hours instead of three or more days as required with current laboratory methods.
Exact mass TOF is a technique for detecting analytes by accelerating ions and measuring mass-to-charge ratio from which molecular weight is determined – giving researchers the benefits of high sensitivity, resolution and accuracy in their detection workflows. The technology was developed for ease of use and for either standalone platform use, or OEM incorporation into other measurement systems.
Stafford O’Kelly, head of molecular diagnostics business at Abbott, said: “Plex-ID addresses the unmet needs and complex challenges of microbial identification by detecting and characterizing both known and previously unknown organisms found in a variety of specimens. Our collaboration with PerkinElmer and their expertise in mass TOF gives us the ability to offer laboratories rapid detection and correct identification of a broad range of pathogens.”
Dick Begley, president of emerging technologies at PerkinElmer, said: “Our relationship with Abbott in pathogen measurement via exact mass TOF complements extensive PerkinElmer programs in environmental applications and research. We are delighted to collaborate with Abbott in this important endeavor for real time microbial identification.”
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