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Pharmacyclics signs CRADA with NCI

Pharmacyclics has entered into a five-year cooperative research and development agreement (CRADA) with the National Cancer Institute (NCI) to develop PCI-32765 as a treatment for hematologic malignancies (blood cancers).

As per the terms of the CRADA, Division of Cancer Treatment and Diagnosis (DCTD) of NCI intends to sponsor PCI-32765 Phase 1 and Phase 2 trials in certain hematologic malignancies, including multiple myeloma and non-Hodgkin lymphoma (NHL).

Pharmacyclics Oncology Development vice president Eric Hedrick said this CRADA represents a major achievement for the company, and allows them to broaden their knowledge of PCI-32765 based on clinical trials to be performed by leading investigators in the field of hematologic malignancies.