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Rigel Obtains Milestone Payment From Daiichi Sankyo

As part of collaboration to research and develop cancer treatments aimed at selectively inhibiting ligases

Rigel Pharmaceuticals (Rigel) has received a milestone payment from Daiichi Sankyo as part of their collaboration to research and develop cancer treatments aimed at selectively inhibiting ligases, which are intrinsic to cancer cell growth and proliferation. The compound, as yet unnamed, targets cell division.

Reportedly, both the companies have an ongoing research collaboration aimed at identifying small molecule drug candidates against a ligase target that controls cancer cell proliferation through protein degradation.

Rigel’s early research efforts uncovered a number of compounds that appeared to inhibit replication of several types of tumor cells. Daiichi Sankyo’s research has advanced some of Rigel’s early work and has resulted in several milestone payments previously announced through this collaboration.

Donald Payan, chief scientific officer of Rigel, said: “We are pleased that Daiichi Sankyo has achieved the milestone and look forward to their efforts in the next upcoming studies and, potentially, future clinical development.”