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Study says OTC NSAIDs do not cause miscarriage

A US study suggests that use of nonprescription over-the-counter (OTC) NSAIDs including painkillers like aspirin, ibuprofen and naproxen in early pregnancy does not put women at increased risk of spontaneous abortion.

The objective of the study was to estimate the association between NSAIDs exposure during the early first trimester and risk for spontaneous abortion (gestation before 20 weeks of gestation) in a prospective cohort.

The study, which was partly funded by the National Institutes of Health, enrolled pregnant women who use NSAID from the last menstrual period (LMP) through the sixth week of pregnancy.

Development stage was determined from ultrasonography study, while gestational age was determined from the LMP.

The study results demonstrated that overall 43% women, who have used the painkillers at the time they conceived or in their first six weeks of pregnancy, reported no abortion.

Study leader Digna Velez Edwards was quoted by nlm.nih.gov as saying that, "We can never know whether NSAIDs or any other medication are completely safe for pregnant women."

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