Takeda Pharmaceutical Company and Amylin Pharmaceuticals have mutually terminated their worldwide agreement signed in October 2009 to co-develop and commercialize anti-obesity compounds.
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In August 2011, the companies decided to suspend the pramlintide/metreleptin investigational combination therapy development.
The decision was based on a commercial re-assessment of the program, which had been in phase II development of a twice-a-day injection formulation.
Japan-based Takeda expects to carry on enhancing R&D activities in the area of obesity in addition to other main therapeutic aspects.