In our laboratory we are able to produce amorphous materials using several techniques such as spray drying, quench cooling, desolvation, etc.
The stability of an amorphous phase is also investigated by solid state NMR and RAMAN spectroscopy techniques and we are able to evaluate the conditions of conversion into the crystalline phase.
The stability of API with temperature, pressure, mechanical stress and humidity is assessed by diffraction, spectroscopic, calorimetric and thermogravimetric methods. Conversion and interconversion of polymorph, amorphous or solvate phases are investigated over a wide temperature range.