CADI™ Models

The CADI™ models are detailed maps of inter-cellular and/or intra-cellular mechanisms associated with a biological status.

• CADI models are outstanding “non-mathematical” descriptive in-silico answers to explain the non-linear mechanisms of life and diseases
• CADI models can describe the dynamics of pathological processes and/or pathological mechanisms vs. control
• CADI models describe the mechanisms that cause the diseases, not only the consequences
• CADI models create the optimum new knowledge required to identify/explain mechanisms that can lead to direct industrial applications
• CADI models have repeatedly led to novel patentable discoveries in highly competitive applications

What can we do with CADI models?

CADI models can reduce time to result, improve success rate and reduce development costs in the following markets: biomedical, chemistry, environment, energy, through:

• Disease understanding / redefinition, targets identification, new therapeutic strategies, new associations of molecules
• Identification/selection of pertinent predictive Biomarkers R&D programs evaluation
• Predictive efficacy and safety profiles, drug (re)positioning /(re)profiling/ rescue. New associations of existing molecules
• Proteins “diversification” engine for improved next generation antibodies, enzymes, and long peptides
• Proposition of new bio-production processes through micro-organisms modifications

CADI “architectural” principles

The efficient and reliable construction of innovative buildings.

• The design phase: Architects conceive and design the building so that it obeys defined functional and structural specifications while integrating within a given environment
• The “blueprint” design phase: The resulting plans are then forwarded to engineering specialists who calculate and/or test components parameters where and as required

The resulting final blueprint is then forwarded to the contractors who then build the structure according to the blueprint specifications.

• In this analogy, BMSystems acts as the “architect” while mathematical modelers and experimentalists play the complementary role of “engineering specialists”
• As with traditional architecture, the results must be solid, useful, convenient and have intrinsic elegance

By keeping to the architect’s point of view and overall design attitude, BMSystems’ scientists are able to succeed and solve unusual problems where traditional methods fail.