Calcipotriol was the first Vitamin D analogue on the market and is licensed for once- or twice-daily use in the treatment of moderate plaque psoriasis.
Calcipotriene
A great deal of activity has been devoted over the past years in order to develop analogues of Vitamin D showing the desired cell differentiating and immunomodulating activity, but with strongly reduced hypercalcemic activity.
It is available as scalp lotion, cream or ointment. The combination of Calcipotriol with a potent steroid (Betamethasone) is more effective and is better tolerated.
Synergy with other treatments, like PUVA, UVB and ciclosporin has been reported in some studies.
Cerbios-Pharma’s calcipotriol anhydrous is complying to the European Pharmacopoeia. EDMF and US-DMF are available, active and updated. An application for the Certificate of Suitability of the European Pharmacopoeia at the European Directorate for the Quality of Medicines (EDQM) was filed recently.
The API is packed in 2mL, 20mL, 50mL or 100mL brown, type 1 glass bottles with rubber closure and aluminium crimp cap.
For more information please see our website, or contact us.
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