Injectable Microspheres

InnoCore's versatile SynBiosys biodegradable multi-block co-polymer platform forms the basis for the development of long-acting, injectable microparticles for systemic and local delivery of active pharmaceutical ingredients.

Relying on micro-encapsulation process technologies developed in-house and through technology partnerships, InnoCore is capable of producing injectable microsphere formulations with controlled particle sizes (typically 20-50 micron) that are suitable for sustained release of active components from a few weeks up to six months. The InnoCore micro-encapsulation processes have proven their success with a variety of pharmaceutical compounds, such as antibiotic drugs and peptides like LHRH-agonists.

Once the product requirements have been defined together with the customer, the most suitable microencapsulation process will be selected as well as relevant formulation parameters to achieve the required drug load, release period, profile and other product characteristics. The architecture of the SynBiosys polymer platform allows encapsulating small and medium-sized pharmaceutical actives with a wide range of release profiles to create tailored drug-loaded microparticles.

So as to create next generation drug delivery microsphere products with competitive features and improved patient compliance, InnoCore has established strategic R&D collaborations focussed on micro-encapsulation process technology for the manufacturing of monodisperse microspheres, microspheres with improved protein stability and continuous manufacturing processes to replace the commercially less viable batch-wise microencapsulation processes.