A breakthrough assay for live cell apoptosis measurement
The nuclear lamina is a meshwork enclosing the entire nucleus – the control center of eukaryotic cells. Its function is to hold together nuclear content and to add mechanical support to the nucleus. The nuclear lamina is a very sensitive subcellular structure. It has to maintain certain rigidity and at the same time allow structural dynamics.
Therefore, artificial incorporation of overexpressed and fluorescently labeled lamin protein mostly leads to undesired cytotoxic side effects. The new Lamin-Chromobody® overcomes these unwanted side effects.
Use the Lamin Chromobody® to:
- Visualize the nuclear lamina without interfering with its cellular functions
- Monitor the nuclear integrity and morphology during live cell microscopy as an indicator for cellular health and viability
- Explore this novel biosensor for real-time assays of mitosis or apoptosis
- Available as stable fluorescent cell line ready to go for cellular screening
- Available as plasmid to allow working with cell line of your choice
Please contact us regarding the Lamin Chromobody® cell line and plasmid.
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