Targeted Libraries

Targeted Libraries are pre-selected subsets of Life Chemicals stock available compounds with potential activity towards certain biological targets. To design the Targeted Libraries both receptor-based and ligand-based approaches were used along with various advanced chemoinformatic techniques such as similarity and substructure searches and virtual docking.

Life Chemicals offers following Targeted Libraries:

• Enzymes Targeted Libraries: Kinases, Proteases, Polymerase, ATPase, Phosphatase, CYP inhibitors
• Sharp Focused Kinases Libraries: FGFR1K, PDK-1, PKA, PI3K, JAK, ROCK, ERK5
• Transporters Targeted Libraries: Ion Channels, Aquaporins
• GPCRs Targeted library
• Protein-protein Interactions Inhibitors
• Epigenetics Targeted Libraries
• Nuclear Receptors Targeted Library
• Activity Targeted Libraries: Antibacterial, Antiprotozoa, Antituberculosis, Antiviral, Anticancer, CNS
• Agro-like Library: Insecticides, Fungicides, Herbicides, Microbiocides
• Natural Product-like Compounds Library
• Covalent Inhibitors Library
• Biologically Active Compounds
• CUTE Targeted Libraries: Nuclear Receptors, aminergic GPCRs, peptidergic GPCRs, "other" GPCRs, Serine Proteases and Kinases