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Methyl-Tetrahydrofolic Acid Calcium Salt

A characteristic property which distinguishes N5-Methyl-Tetrahydrofolic Acid from the other reduced folates is that it can cross the blood brain barrier. This has implications in the case of treatment for depression, for example.

Synonyms

• (6RS)-N5-Methyl-5,6,7,8-Tetrahydrofolic Acid Calcium Salt
• Calcium Mefolinate

Regulatory compliance

A DMF is available.

Intellectual property

• A method of purification of N5-Methyl-tetrahydrofolic acid calcium salt is patent protected (CH 682 665)
• Ammonium salts of N5-Methyl-tetrahydrofolic acid are patent protected (EP 455 013)

Packaging information

The active ingredient is packed in a low density polyethylene bag inside a high density polyethylene aluminium bag, which in turn is packed in a high density polyethylene container (of up to 64 litres). Variable quantities of API per container are available.

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