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Pharmaceutical Technologies for Optimal Drug Delivery Solutions

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Technologies for New Formulations

Our broad platform of oral pharmaceutical technologies are available for co-development of new product formulations across multiple therapeutic categories. Our formulation expertise allows us to utilize our platforms alone or in combination to develop enhanced Rx or OTC products with differentiated features and benefits for patients.

Technology Platforms include:

Custom Drug Release Technologies – Diffucaps®: A multiparticulate customized drug release system that provides flexible dosage strength and optimal PK profiles for single drugs, pH-sensitive drugs, and drug combinations.

Tastemasking Technologies– Microcaps®: Employs versatile and precise coating techniques to encapsulate individual drug particles using solvent- or aqueous-based coacervation, resulting in superior taste masking, customized release profiles, conversion of liquids to solids and the separation of incompatible materials.

AdvaTab®: Advanced orally-disintegrating tablet technology enabling rapid disintegration in the mouth, without water, and proven bioequivalent to immediate release formulations. Can be combined with Microcaps® or Diffucaps® technologies to develop robust tablets with smooth mouth feel and custom release profiles.

Bioavailability Enhancement Technology – Biorise®: — improves the rate and extent of absorption of drug in oral dosage forms, resulting in effective oral dosing of poorly water soluble compounds, equivalent therapy at lower doses, faster onset of action, and/or minimization of food effect.

Available Products for Licensing (Commercially Ready Formulations)

Nutrition:

  • Potassium Chloride 600mg/8mEq capsules
  • Vitamin C 500mg Extended Release Capsules. Available also as a food supplement (any dose)

Pain:

  • Cyclobenzaprine (once-daily) Extended Release 15mg and 30mg capsules
  • Diclofenace Sodium (once-daily) Extended Release 75mg and 100mg capsules

Sleep Aid:

  • Diphenhydramine HCl 25mg Orally Disintegrating Tablets

For a full list of available products for out-licensing, please visit our website at www.AptalisPharmaTech.com

Product Highlights:

Development Stage Products Available for Out-Licensing: #

Contact a representative about available opportunities with these products

AdvaTab® Paracetamol (Acetaminophen) Orally Disintegrating Tablets: Commercially- ready pain product utilizing Microcaps® tastemasking technology available in a fast-dissolve tablet.

Diffucaps® Ondansetron ER (once-daily) Capsules: Extended release capsules to treat emesis; pivotal efficacy stage.

AdvaTab® Temazepam Orally Disintegrating Tablets: Sleep-aid available in a fast-dissolve tablet; pivotal biostudy stage.

AdvaTab Hydrocodone + Paracetamol Orally Disintegrating Tablets: Combination pain product utilizing Microcaps® tastemasking technology available in a fast-dissolve tablet; pivotal biostudy stage

AdvaTab Cetirizine Orally Disintegrating Tablets: Allergy product utilizing Microcaps® tastemasking technology available in a fast-dissolve tablet; pilot biostudy stage

AdvaTab Topiramate Orally Disintegrating Tablets: Early-stage formulation to treat epilepsy, utilizing Microcaps® tastemasking technology available in a fast-dissolve tablet.

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