Proteomics and Metabolomics

Proteomics

Fios Genomics offers a wide range of services for the analysis of data generated by state-of-the art proteomics technologies, such as Shotgun LC-MS/MS, SELDI-TOF MS and MALDI-TOF MS and protein arrays. Proteomics is the study of the full repertoire of proteins encoded by the genome in a given cell, tissue or organism. It is used to further our understanding of protein structure and function and how these change in response to disease. Using our knowledge of proteomics technologies and expertise in the computational sciences we can provide unparalleled services for the analysis and interpretation of proteomics data. We can process data from advanced proteomic platforms for the purposes of:

• Biomarker identification
• Protein identification and quantification
• Protein complex identification
• Protein discovery
• Protein profiling

Metabolomics

Metabolomics is a specialised form of analytical biochemistry that enables the global analysis of endogenous metabolites, including chemical intermediates, hormones and lipids present in bodily fluids and tissues. Metabolites can be identified by a combination of LC-MS and NMR, which produce metabolic profiles or fingerprints. Metabolomics enables better characterisation of biological systems and may have application in the diagnosis and prognosis of disease and in the evaluation of new therapies. Our metabolomics services include:

• Metabolite profiling
• Metabolite identification
• Metabolite quantification