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Sulfoximines for Drug Design

Incorporation of a sulfoximine group into bioactive compounds often improves their ADME/Tox profile and enhances potency. Moreover, the moiety of sulfoximine is chemically and metabolically stable. NH-sulfoximines can serve as both hydrogen bond donors and acceptors at the same time.

Production and commercialization of the building blocks that already contain a sulfoximine group allow significant accelerating discovery of drug candidates. Herein we have designed and synthesized a library of sulfoximines for drug design.

We offer >100 unique sulfoximines on a 5-50 g scale from stock.

Design and full list you can find at MedChem Highlights section of Enamine’s website or in the white paper attachment.