This article is aimed to offer a general review of the fixed-dose combinations (FDC) and manufacturing technologies, highlighting their applications, benefits and setbacks.

It also includes a case study to illustrate the product concept based on the technological platform of Unigel® for FDCs in soft gelatin capsules.

In the case study, FDC systems were mainly aimed to increase patient compliance to the pharmacological treatments composed of two or more active drugs in a single dosage form in order to decrease the number of doses and the prescription problems.

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