Clinical TrialsHuman Trials March 31, 2020 Noveome to assess ST266 to treat severe inflammatory response linked with COVID-19 By PBR Staff Writer According to the company, the new programme is based on data showing that ST266 significantly decreased the inflammatory response of a body in a range of diseases and
Drug DiscoveryResearch & Development March 30, 2020 Sanofi, Translate Bio to develop novel mRNA vaccine for COVID-19 disease By PBR Staff Writer The latest deal is said to leverage an existing agreement between the two companies established in 2018 for the development of mRNA vaccines for infectious diseases. Translate Bio
Drug DiscoveryResearch & Development March 26, 2020 Xencor, Vir Biotechnology collaborate on Xtend XmAb antibody technology for COVID-19 By PBR Staff Writer Under the deal, Vir can non-exclusively access Xencor’s Xtend Fc technology to expand the half-life of novel antibodies, which are being assessed as potential treatments for patients with
Clinical TrialsHuman Trials March 20, 2020 Roche to begin Actemra/RoActemra trial with COVID-19 pneumonia patients By PBR Staff Writer The company is working with the US Food & Drug Administration (FDA) to commence a randomised, double-blind and placebo-controlled phase III clinical trial in collaboration with the Biomedical
Drug DiscoveryResearch & Development March 18, 2020 Pfizer, BioNTech collaborate to develop vaccine for COVID-19 By PBR Staff Writer Under material transfer and collaboration agreement, the companies will co-develop and supply potential mRNA-based coronavirus vaccine for the prevention of COVID-19 infection. The vaccine will not be supplied
RegulationDrug Filing February 17, 2020 Epizyme seeks FDA accelerated approval for Tazverik to treat follicular lymphoma By PBR Staff Writer The regulator has accepted the firm’s new drug application (NDA) for the accelerated approval of tazemetostat to treat patients with relapsed or refractory FL who have secured at
Drug DiscoveryResearch & Development February 10, 2020 Roche’s gantenerumab fails to meet primary endpoint in AD trial By PBR Staff Writer The gantenerumab arm of phase II/III DIAN-TU-001 study has failed to meet its primary endpoint in people who have an early-onset, inherited form of AD or otherwise known
Clinical TrialsHuman Trials January 23, 2020 Roche’s risdiplam achieves primary endpoint in infant-related spinal muscular atrophy trial By PBR Staff Writer The company has reported positive topline results from the pivotal part 2 of the FIREFISH study, which is assessing risdiplam in infants aged between one and seven months
Drug DiscoveryResearch & Development January 20, 2020 Clarivate Analytics to buy Decision Resources Group for $950m By PBR Staff Writer DRG is engaged in offering high-value data, analytics and insights products and services to the healthcare industry. The deal includes $900m in cash, as well as issuing of
Drug DiscoveryResearch & Development January 13, 2020 Eli Lilly to buy biopharmaceutical firm Dermira for $1.1bn By PBR Staff Writer Based in Menlo Park of California, Dermira is involved in the development of novel therapies to treat patients with chronic skin conditions. As per terms of the deal,