Production & SalesManufacturing December 7, 2018 AstraZeneca divests asthma and rhinitis drug rights to Covis Pharma By PBR Staff Writer The divested rights by the UK-based AstraZeneca to Covis Pharma cover markets outside the US and the US royalties for the three over-the-counter (OTC) drugs. In 2017, AstraZeneca
Drug DiscoveryResearch & Development December 4, 2018 GSK to buy oncology-focused biopharmaceutical firm Tesaro for $5.1bn By PBR Staff Writer Based in Waltham of Massachusetts, Tesaro is a commercial-stage firm engaged in the development of advanced therapies to treat cancer. As per the terms of the deal, GSK’s
RegulationApprovals November 29, 2018 Teva, Celltrion get FDA nod for biosimilar to Roche’s cancer drug Rituxan By PBR Staff Writer Truxima, a monoclonal antibody (mAb), has been approved to treat adult patients with relapsed or refractory, low-grade or follicular, CD20-positive, B-cell non–Hodgkin’s lymphoma (NHL) as a single agent.
Drug DiscoveryResearch & Development November 28, 2018 Roche’s Genentech agrees to buy Jecure Therapeutics By PBR Staff Writer Based in San Diego of California, Jecure Therapeutics is engaged in the discovery of therapeutics to treat non-alcoholic steatohepatitis (NASH) and liver fibrosis. Jecure Therapeutics president and CEO
Clinical TrialsPatient Enrollment November 9, 2018 4D pharma begins patient enrollment in Blautix IBS phase II study By PBR Staff Writer The company has randomized the first patient of the mid-stage trial which will assess the efficacy and safety of Blautix in patients having IBS with constipation (IBS-C) and/or
Clinical TrialsHuman Trials September 7, 2018 Gilead and Galapagos’ filgotinib succeeds in ankylosing spondylitis trial By PBR Staff Writer Filgotinib, an investigational and selective JAK1 inhibitor, has achieved its primary efficacy endpoint in adults with moderately to severely active AS in the phase 2 Tortuga study. AS
Drug DiscoveryDrug Manufacturing September 6, 2018 Aurobindo to buy parts of Sandoz US from Novartis for $900m By PBR Staff Writer Under the agreement, Aurobindo will purchase Sandoz US dermatology business and generic US oral solids portfolio. As part of the deal, Aurobindo will acquire manufacturing facilities in Wilson
RegulationApprovals August 17, 2018 Merck, Eisai win FDA approval for Lenvima to treat unresectable HCC By PBR Staff Writer The approval was based on data from Reflect study, which showed Lenvima’s treatment effect on overall survival (OS) by statistical confirmation of non-inferiority and also improved progression-free survival
Drug DiscoveryResearch & Development August 16, 2018 Pfizer, BioNTech to develop mRNA-based vaccines for influenza By PBR Staff Writer Under the deal, the partnership will carry out research and development activities for the advancement of mRNA-based flu vaccines. BioNTech co-founder and CEO Dr Ugur Sahin said: “Today’s
Drug DiscoveryResearch & Development August 15, 2018 Haplogen, Bayer enter into drug discovery and development collaboration By PBR Staff Writer Based in Vienna, Austria, Haplogen is a biotechnology company focused on developing therapeutic substances for the treatment and prevention of infection by the common cold virus. The multi-year