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Roche offers new metabolite tests for mammalian cell fermentation analytics

Roche is offering new metabolite tests for its Cedex Bio Systems, which are designed for applications in research and bio-manufacturing process development.

Developed to determine iron and phosphate concentrations, the tests allow the measurement of iron (complexed iron /Fe3+ ions) and phosphate on Cedex Bio instruments.

Iron and phosphate are two parameters relevant for cell growth and productivity during fermentation processes.

Roche biochemical reagents and custom biotech head Ruedi Stoffel said the new tests expand the metabolite testing portfolio for mammalian cell fermentation analytics.

"It is currently the most comprehensive portfolio combining iron and phosphate testing with other relevant parameters such as IgG, LDH and other standard metabolites," Stoffel added.

"Thanks to their reliability, precision, and ease of use, our Cedex instruments and the new testing portfolio are perfectly designed to optimize process development and monitoring of bio-pharmaceutical production particularly when using chemically defined media."

With increased precision, accuracy and long calibration intervals, the new tests can be installed by barcode reading through the customer supporting the flexible testing concept, according to the company.

The new iron and phosphate tests do not require manual dilution or pipetting steps and are available as liquid-stable formulation.