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news.Roche NimbleGen, a developer of products and services for the analysis of genomes, has expanded its growing line of tools for analyzing the epigenome and genome-wide transcriptional regulation mechanisms by launching HD2 arrays and services for chromatin immunoprecipitation.
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According to the company, chromatin immunoprecipitation (ChIP-chip) HD2 arrays now provide more than a five-fold increase in probe density per array, which allows for increasing the coverage of key biological features, such as promoters and CpG islands, and decreasing the number of arrays needed to perform whole-genome analysis at high resolution.
Customers can access NimbleGen ChIP-chip HD2 arrays by ordering arrays, instrumentation, and software and performing the research in their laboratory or core facility or by simply submitting immunoprecipitated and input samples to the Roche NimbleGen service facility for full service analysis, the company said.
The Human Deluxe Promoter array allows researchers to interrogate all known and alternative start site promoters at 10kb promoter coverage, all annotated CpG islands (~28,000), and ~500 miRNA promoters on a single glass slide.
Bing Ren, epigenomics and genomics researcher of the Ludwig Institute, University of California, San Diego School of Medicine, said: “NimbleGen ChIP-chip high-definition 2.1 million probe arrays are a flexible and robust platform for investigating the transcription factor binding sites and chromatin modification patterns in the genome of a variety of model organisms and have been extremely valuable for our research of the transcriptional regulatory elements in the drosophila, mouse and human genomes.”