MacroMed licenses anticancer product to Diatos

In addition, Diatos has also received rights to sublicense OncoGel and to develop and commercialize second generation OncoGel products.

Diatos and MacroMed, both privately held biopharmaceutical companies, will collaborate on the clinical development of OncoGel, sharing data from clinical trials conducted in their respective territories.

The two companies intend to develop OncoGel for treatment of several types of solid tumors, which may include breast, lung, esophageal, head and neck, brain, liver, colon, pancreas and ovarian cancers. OncoGel is currently in phase II clinical trials in the US for esophageal cancer.

Under the terms of the agreement, Diatos will pay MacroMed a license fee, milestone payments, and royalties on product sales. In addition, MacroMed has retained the right to provide the majority of clinical and commercial supplies of OncoGel to Diatos.

OncoGel is an injectable, controlled-release formulation of paclitaxel, the active ingredient in Bristol-Myers Squibb’s Taxol. Once injected, OncoGel maintains a high, long-term intra-tumoral concentration of paclitaxel with minimal systemic exposure which may make it ideal for neoadjuvant, adjuvant and palliative treatment settings.

OncoGel therapy may also prove to be effective in various types of tumors, including Taxol-resistant tumors and in tumors with long cell division cycles.

MacroMed’s CEO, Thomas Bergmann, stated, “We are very pleased to have the opportunity to work with Diatos to develop and commercialize this exciting product worldwide. We have confidence in Diatos’s expertise to continue OncoGel’s development in Europe and initiate new development in Asia, while allowing us to focus our resources on development in the US.”