TRON (Translational Oncology at University Medical Center Mainz) has adopted Ingenuity Systems' Ingenuity Variant Analysis to identify cancer driver variants that inform the development of an experimental individualized RNA-based therapeutic.
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Ingenuity Variant Analysis is a web application that enables researchers to identify causal variants from human resequencing data in a short time period using known information about the biological effects of variants.
Ingenuity is said to have leveraged the Ingenuity Knowledge Base of accurate, curated biological content and comprehensive database of curated mutation information to develop Ingenuity Variant Analysis.
Ingenuity Variant Analysis, which is currently available in limited access, enables researchers to quickly sift through many variants to identify a few causal variants based upon known relationships with pathways, genes, biological processes, and diseases.
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