Helsinn Healthcare and Eisai have announced the availability in the US of Aloxi injection 0.075mg for the prevention of postoperative nausea and vomiting for up to 24 hours following surgery.
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Approved by the FDA for postoperative nausea and vomiting, Aloxi injection 0.075mg is administered as a single IV dose immediately before induction of anesthesia to prevent PONV for up to 24 hours following surgery. Efficacy beyond 24 hours has not been demonstrated.
Aloxi has been available in the US since 2003, when it was approved by the FDA for the prevention of chemotherapy-induced nausea and vomiting (CINV). A supplemental new drug application for Aloxi capsules for oral administration for CINV is currently under review by the FDA.
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