Atlab Pharma has entered into a sublicense agreement with BZL Biologics for developing 177Lu-J591, a radiopharmaceutical product used to treat cancer.
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The agreement comprises exclusive rights to manufacture, develop and commercialize the drug candidate across the globe, besides a joint Phase IIB/III clinical validation program.
In addition, Atlab Pharma will also fund certain product development and clinical trials.
Lu-J591, a tumor-specific delivery system comprises humanized J591 monoclonal antibody targeting prostate-specific membrane antigen (PSMA) in addition to the 177Lu radioisotope.
Phase I and Phase II trials comprising 108 patients with metastatic castrate-resistant prostate cancer, demonstrated efficacy and tolerability of 177Lu -J591.
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