Durect has concluded patient dosing in Bupivacaine Effectiveness and Safety in Saber trial (BESST) Phase III trial evaluating Posidur, a post-operative pain relief depot that uses Durect's patented Saber technology to deliver bupivacaine to provide up to three days of pain relief after surgery.
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The trial is to investigate the efficacy, effectiveness, safety and pharmacokinetics of Posidur in 305 patients undergoing a variety of general abdominal surgical procedures.
Durect expects to report top-line data from the BESST trial in the fourth quarter of 2011.
Durect has licensed Posidur to Hospira for commercialization in the US and Canada.
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