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Japan Tobacco, Torii Pharma initiate Zerenex Phase 3 trial

Keryx Biopharmaceuticals' partners Japan Tobacco (JT) and JT's pharmaceutical business subsidiary, Torii Pharmaceutical have started a Phase 3 clinical trial in Japan to evaluate ferric citrate to treat patients with hyperphosphatemia.

Earlier in September 2007, Keryx sublicensed the exclusive rights for the development and commercialization of hyperphosphatemia drug Zerenex (ferric citrate) to JT and Torii in Japan.

As a result of initiation of the Phase 3 trial, JT/Torii are responsible to pay a non-refundable milestone payment of $5m to Keryx for the achievement of this milestone.

Keryx CEO Ron Bentsur said they congratulate JT/Torii, on the initiation of the Phase 3 program in Japan and are excited by their progress.

"We believe that this serves to further validate the commercial potential for Zerenex worldwide," Bentsur said.