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news.Bend Research has received US patent for technology that uses polymer additives to enhance the bio availability of low-solubility drugs in the human body.
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The technology works by sustaining high concentrations of drug in the gastrointestinal tract.
The patent, which is titled ‘Pharmaceutical Compositions Comprising Drug and Concentration-Enhancing Polymers,’ complements a number of patents that use spray-drying to create amorphous dispersions.
Drug forms covered by the patent are nanoparticles, absorbed drugs, drugs in nanosuspensions, supercooled drug melts, cyclodextrin/drug forms, gelatin dosage forms and soft-gel dosage forms.
The patent is one in a growing number of formulation- and process-related patents associated with Bend Research’s solubility-enhancing drug-formulation technologies.
These solubilization technologies enhance the concentration of drug in patients’ bloodstreams and enable faster drug dissolution than is possible with crystalline drug forms.
Bend Research provides formulation and dosage-form support, assists in process development and optimization, manufactures clinical-trial quantities of drug candidates in its cGMP facility, and advances promising drug candidates from conception through commercialization.