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news.US based Metametrix Clinical Laboratory has introduced the urinary neopterin/biopterin profile.
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This latest testing profile measures the oxidative products of tetrahydrobiopterin (BH4). Neopterin and biopterin are by-products of the redox reactions involving tetrahydrobiopterin (BH4).
From a simple overnight urine collection, the test measures neopterin, biopterin, a ratio of the two, as well as creatinine to allow detection and monitoring of BH4. Supplementation and treatment plans can then be implemented to improve BH4 enzyme deficiencies.