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news.Opko Health and Pathogenics have reported positive preclinical data demonstrating the potential therapeutic utility of their proprietary formulation of N-Chlorotaurine or NCT in the treatment of Acanthamoeba keratitis, a serious eye infection.
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The study showed that, in vitro, NCT clearly demonstrated amoebicidal activity at concentrations that are likely to be well tolerated in humans.
Study also reported that co-treatment with ammonium chloride appeared to further enhance NCT’s anti-parasitic activity, including its activity against Acanthamoeba cysts, resulting in the complete loss of viability of the infection-causing parasites.