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Alvine granted patents for celiac disease therapies

Alvine Pharmaceuticals said that the US Patent and Trademark Office has granted two key patents covering celiac disease therapies.

These patents will cover gluten detoxification with proline specific prolyl endopeptidases (PEPs) and with mixtures of a PEP and a glutamine specific protease.

Alvine has an exclusive worldwide license to these patents under an agreement with Stanford University. Both patents provide important protection for ALV003, Alvine’s lead product currently in clinical development for use in the treatment of celiac disease.