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PharmAthene and Siga to merge

Biodefense companies PharmAthene and Siga Technologies have signed an agreement to merge with each other. Financial terms of the deal were not disclosed.

The combined company, which will operate under the “PharmAthene” name, is expected to be a leader in biodefense featuring a substantial portfolio of procurement-stage biodefense products targeting anthrax, smallpox and chemical nerve agents, as well as a robust pipeline of therapeutic and prophylactic drug candidates targeting “category A” biowarfare agents and emerging infectious diseases.

The combined company’s biodefense portfolio will include, ST-246, a small molecule orally-active antiviral therapeutic for the treatment of smallpox and other orthopox virus infections, Valortim, a fully human monoclonal antibody being co-developed with Medarex for the prevention and treatment of anthrax infection, and Protexia a novel bioscavenger to prevent and treat organophosphate nerve agent poisoning.

“Combining PharmAthene’s strong development and commercialization capabilities and procurement-stage biodefense products with Siga’s procurement-stage smallpox antiviral treatment, ST-246, and exceptional research pipeline, establishes a premier biodefense organization with multiple procurement-stage products with near-term revenue potential, and a broad research pipeline focused on biodefense and emerging infectious diseases,” said David Wright, president and CEO of PharmAthene.