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news.Ono Pharmaceutical and Medarex have entered into a collaborative agreement to research and develop a fully human anti-SDF-1 antibody for the potential treatment of multiple indications.
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This is the second antibody development collaboration between Ono and Medarex. Anti-SDF-1 antibodies have been raised utilizing Medarex’s UltiMAb human antibody development system.
Under this collaboration, Ono and Medarex expect to jointly work toward potential commercialization of a fully human antibody. The two companies plan to share the costs and responsibilities of research and product development up to the completion of a phase II clinical study.
Thereafter, each company will be fully responsible for any continued development and any commercialization in its exclusive territory; Medarex’s exclusive territory is North America, and Ono’s exclusive territory is all areas outside of North America.
“We are pleased to work with Ono as we continue to develop MDX-1106, our anti-PD1 antibody product candidate, and now for the development of a potential anti-SDF-1 antibody product candidate,” said Dr Donald Drakeman, president and CEO of Medarex.