Callisto Pharmaceuticals has expanded of its ongoing phase I/IIa clinical trial of L-Annamycin to treat adult patients with relapsed or refractory acute lymphocytic leukemia.
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The expanded trial will now utilize an additional clinical trial site, the Montefiore Medical Center, New York, a leading cancer research center in the US
“Montefiore Medical Center is a preeminent institution for the study of cancer, and we are very gratified that this site has joined the clinical trial of L-Annamycin, providing an additional pool of potential patients for the present study,” said Dr Donald Picker, Callisto’s executive vice president of R&D.
In previous animal studies, L-Annamycin has demonstrated that it can kill tumor cells that are resistant to other anthracycline anticancer drugs. In addition, earlier studies have shown that L-Annamycin may have other key advantages over other anthracycline drugs, including a decreased risk of treatment-related cardiomyopathy (inflammation of the heart muscle), a complication associated with this family of anticancer drugs.