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ChemAxon Enters Into Agreement With Pfizer

ChemAxon has entered into an agreement with Pfizer to provide its Markush searching and structure enumeration functionality for global development and deployment within Pfizer's global R&D facilities.

A Markush structure is a description of a compound class by generic notations, primarily used in patent claims and the description of combinatorial libraries. The library of a Markush structure is the total set of specific molecules that are described by the Markush structure.

The company said that the Markush enumeration plugin can be used to generate a whole or a subset of the library of a generic Markush structure. It is also capable of calculating the total number of specific structures present in a Markush library.

The plugin handles the following combinatorial Markush features: R-groups, atom and bond lists, link nodes, repeating units, position variation bonds and homology variation.

Alex Drijver, CEO of ChemAxon, said: Markush structure search and enumeration is becoming of critical importance for structure IP and patent development. It is an area where ChemAxon has developed a high area of expertise and where we are moving very much into the forefront.