The TrialMax Synapse™ open interface integrates ePRO data collected with CRF Health’s TrialMax® platform to other eClinical
systems in real time using the CDISC ODM standard. The current studies integrated to a leading EDC system are seeing a
variety of benefits, including the enabling of sites to view all study data in one system, increasing the efficiency of drug
accountability, facilitating data management, and allowing easier correlation of adverse events.

Rachael King, CEO of CRF Health, comments, "We have seen a significant increase in interest for integrating ePRO data to
other eClinical systems, and are currently using integration in several studies. As the use of integration has exceeded all of
our expectations, we decided to offer the possibility to all Sponsors and CROs that we are working with."

The TrialMax Synapse™ open interface offers efficient tools for setting up and maintaining integration in individual clinical
studies, according to their specific needs. Pekka Keskiivari, Chief Technology Officer, continues, "Real time integration of
study data is the future of eClinical. By using good technology along with relying on standards, we can make the deployment
very straightforward. In the future, integration will be an expected part of setting up a trial."