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TissueGene begins clinical testing for joint disease drug

Biopharmaceutical company TissueGene has initiated a phase I clinical trial evaluating a single dose of its investigational compaound TG-C for the treatment of degenerative joint diseases.

This clinical trial is designed to assess the safety of TG-C in patients who have opted for total knee arthroplasty.

TissueGene has developed TG-C to regenerate cartilage in patients suffering from degenerative arthritis and more specifically for indications such as osteoarthritis of the knee. As an alternative to other methods of cartilage repair, TG-C will involve minimally invasive injections versus a surgical approach. Other techniques currently involve multiple and often invasive surgical procedures and have mixed results.

“We are pleased with the approval to start our phase I program with TG-C and feel that our drug candidate has the potential to be not first-in-class, but also best-in-class,” stated Dr K.H. Lee, president, founder and CEO of TissueGene.