Roche and GE Healthcare collaborate in Alzheimer’s trial

In controlled clinical trials, patients taking a Roche anti-amyloid drug candidate for Alzheimer’s disease will be monitored clinically for drug response using GE’s positron emission tomography (PET) diagnostic imaging agent.

This proprietary PET technology measures and tracks levels of beta-amyloid, a form of brain plaque believed to cause memory loss in Alzheimer’s disease patients. Previously, the presence of plaque could only be confirmed during autopsy.

Both Roche and GE will independently analyze patient data to monitor the progression of the disease and then share information to validate the efficacy of both the therapeutic product and the diagnostic tool. The data gathered will aid both companies in submitting necessary and comprehensive data to regulatory authorities for approvals.

“This collaboration is an early step in experimental medicine,” said Peter Hug, Roche’s Global Head of Pharma Partnering. “Using GE’s innovative technology allows Roche to test the efficacy of our product more accurately than was previously possible, which in the long term, will help us efficiently advance through clinical development, potentially helping patients sooner.”