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Salt Screening Programs

SARA Pharm Solutions

SARA PHARM's salt screen program is a comprehensive search for pharmaceutically acceptable salts of ionizable drug substances using pharmaceutically acceptable counter ions (e.g acids or bases), knowledge of their physico-chemical properties, their frequency of use in drug products (e.g Orange Book), as well as their processability.

The need to use a salt is based on poor API drug substance properties such as lack of crystallinity, water solubility, or physical/chemical stability.

SARA PHARM designs the salt screening program based on the desired enhancement of API properties, using well-defined ways to quickly identify the salts with optimum properties. With this clear purpose SARA PHARM makes use of its comprehensive database of counter ions with their fully physico-chemical properties.

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