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Cyclic sulfates and sulfamidates as alkylating reagents

Cyclic sulfates and sulfamidates are precursors for the synthesis of alkyl chains bearing sulfur, nitrogen and oxygen functionalities. Medicinal chemists often use them as alkylating reagents. A wide variety of chemically and biologically important molecules have been prepared from cyclic sulfates and cyclic sulfamidates. Herein, we have designed and synthesized a library of cyclic sulfates and sulfamidates for medicinal chemistry projects.

You can find the full list at MedChem Highlights section of Enamine’s website or in the white paper attachment.