Epoxides are important heterocyclic units found in various naturally occurring molecules, some with potential bioactivities.
At least fourteen drugs on the market are epoxide-containing.
In addition, epoxides are valuable building blocks in medicinal chemistry. They react with nucleophiles in a ring-opening process to form new C-C, C-O and C-N bonds.
We have designed and synthesized a library of small heteroaliphatic epoxides for drug design, which you can find at MedChem Highlights section of Enamine’s website.