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Epoxides for Drug Design

Epoxides are important heterocyclic units found in various naturally occurring molecules, some with potential bioactivities.

At least fourteen drugs on the market are epoxide-containing.

In addition, epoxides are valuable building blocks in medicinal chemistry. They react with nucleophiles in a ring-opening process to form new C-C, C-O and C-N bonds.

We have designed and synthesized a library of small heteroaliphatic epoxides for drug design, which you can find at MedChem Highlights section of Enamine’s website.