The organic chemistry of the pentafluorosulfanyl group (SF5) has been known since the 1950s. As the SF5-group is larger and more lipophilic than the CF3-one, it is often considered as a ‘super-trifluoromethyl group’. Over the past decade, the SF5–containing organic compounds already found great practical application in argochemistry and medicinal chemistry.
- One of the most electron-withdrawing groups
- high chemical and thermal stability
- high lipophilicity
> 30 SF5-buiding blocks in gram amounts in stock. Custom synthesis of analogues and compound libraries