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September 3, 2015

New at PITTCON 2015 – Multiple X-ray Technologies Integrated in Groundbreaking Zetium Spectrometer from PANalytical

In a significant announcement at Pittcon 2015, PANalytical has revealed a revolution in X-ray fluorescence spectrometry. With up to three...
pharmacuetical business review
September 3, 2015

PANalytical Launched new Compact Benchtop XRF System for Pharmaceutical Catalysts Analysis

PANalytical launched a new Epsilon 1 XRF (X-ray fluorescence) analyzer at last year’s meeting of the American Association of Pharmaceutical...
pharmacuetical business review


PANalytical, Epsilon 1 Pharma.


PANalytical offers a wide range of key analytical techniques and products that are used in the pharmaceutical industry for research, development and quality control purposes. These rapid non-destructive analytical techniques such as near-infrared spectroscopy (NIR), X-ray diffraction (XRD) and X-ray fluorescence spectrometry (XRF) can be used for a large variety of (bio-)pharmaceutical applications including drug discovery, pre-formulation, formulation, stability testing and final product quality control.

PANalytical products and solutions provide the pharmaceutical industry with analysis methods for elaborate material characterization and also help the industry to meet strict regulatory requirements.

Meeting the needs in drug development and quality control

panalyticalSpeed, reproducibility, ease of use and the adherence to the demands of a highly regulated environment are key requirements for routine pharmaceutical applications. Many X-ray analytical tools have earned their place in today’s pharmaceutical development laboratories, especially in the areas of pre-formulation and formulation of solids. The non-destructive nature of the analyses often allows a multitude of process steps to be performed on the same sample without destroying its original structure.

Standardization and regulation have been embraced by the pharmaceutical community. Instruments used in this environment must provide secure operation, data validation and data traceability.

PANalytical offers a comprehensive portfolio of X-ray diffraction (XRPD) and X-ray fluorescence (XRF) instruments and related modules that are invaluable in areas of interest such as full characterization of active pharmaceutical ingredients (API), both small molecule and biologics, and excipients.

Non-destructive material characterization and analysis solutions

Rapid non-destructive characterization is possible for all material types, including fine chemicals, active pharmaceutical ingredients (API) (small molecules and biologics), excipients (organic and inorganic) and final drug products.

Pharmacopeial X-ray techniques

Internationally recognized pharmacopeial methods (both XRD and XRF) combined with technological developments such as ultra-fast, high-resolution detectors allow X-ray techniques to be at the forefront of (bio-)pharmaceutical development reducing analysis time while providing in-depth analysis of the sample.

PANalytical’s comprehensive expertise gives you an advantage:

  • X-ray analysis methods are comprehensive and proven, with 21 CFR Part 11 Audit Trail compliant solutions for both X-ray powder diffraction (XRPD) and X-ray fluorescence spectrometry (XRF)
  • PANalytical provides a suite of tools such as in-house Expertise for Installation Qualification (IQ), Operational Qualification (OQ) and validation assistance (Design Qualification (DQ) / Performance Qualification (PQ))
  • PANalytical Support – global 24-7 network assistance anytime, anywhere

PANalytical’s headquarters are in Almelo, the Netherlands. Fully equipped application laboratories are established in Japan, China, the US, Brazil, and the Netherlands. PANalytical is active in all but a few countries of the world. This worldwide sales and service network ensures unrivalled levels of customer support.

With a broad product portfolio and an extensive collection of patents and proprietary technologies, PANalytical continuously creates and sustains a distinct competitive advantage.

PANalytical is part of Spectris plc, the productivity-enhancing instrumentation and controls company.

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PANalytical B.V.
Lelyweg 1
The Netherlands
Tel.: +31 546 534444
Fax.: +31 546 534598

Quick Contact PANalytical


ASD LabSpec® bench analyzers

The LabSpec® line of laboratory instrumentation offers laboratory-grade performance in a ruggedized, portable design suitable for benchtop analysis or online analysis. LabSpec analytical instrumentation performs rapid, non-destructive materials analysis for qualitative and quantitative applications.The LabSpec 4 product line employs the same spectrometer configurations as ASD's FieldSpec line of spectroradiometers, long recognized as the "gold standard"…


Empyrean is a truly multi-purpose research X-ray diffractometer. It is like no other system available. The Empyrean platform is designed for now, and for years to come. It is PANalytical’s answer to the challenges of modern pharmaceutical research and development, where the lifetime of a diffractometer is considerably longer than the duration of any single research project. Whether it be high-throughput screening (HTS) small angle X-ray scattering (SAXS), pair distribution function (PDF), or non-ambient analysis the Empyrean is flexible to meet your needs.

Installation Qualification (IQ) and Operational Qualification (OQ) are available and the Audit Trail software can be configured to support 21 CFR Part 11 compliance.

Epsilon 1 Pharma

Pharmaceutical catalyst residue analysis at the push of a button

Looking for an accurate and fast instrument for the cost-effective analysis of pharmaceutical catalyst residues? The Epsilon 1 benchtop X-ray fluorescence (XRF) spectrometer is the ideal analytical solution for quantification of ruthenium, rhodium, palladium, iridium, and platinum in many pharmaceutical materials. Considerable savings in time and cost are two of the many benefits XRF can…

Epsilon 3×

The Epsilon 3× instrument is a benchtop energy dispersive X-ray fluorescence (EDXRF) spectrometer, powered by the latest advances in X-ray tube excitation and SDD detection technology.

Ready for any sample typeThe Epsilon 3× can handle a large variety of sample types, including solids, pressed and loose powders, liquids and filters, from a few milligrams to larger bulk samples. It can perform non-destructive quantitative analysis of elements from sodium to americium, in concentrations from 100% down to ppm levels. Key pharmaceutical applications…

Epsilon 5

A fully integrated floorstanding energy dispersive X-ray fluorescence (EDXRF) spectrometer, the Epsilon 5 combines advanced elemental excitation capabilities with sophisticated instrument control and analytical software. Epsilon 5 provides high-performance trace elemental impurity analysis ideal for USP and ICH Q3D applications.

Installation Qualification (IQ) and Operational Qualification (OQ) are available and the Enhanced data security software can be configured to support 21 CFR Part 11 compliance.

X’Pert³ Powder

A cost-effective, multipurpose X-ray diffraction platform.

The X'Pert³ Powder system offers a solution for high-throughput, high-quality phase identification and quantification, small-angle X-ray scattering, pair distribution function analysis and non-ambient diffraction. The system complies with the latest and most stringent X-ray and motion safety norms and with its eco-friendliness and reliability the X'Pert³ Powder is ready for the future.Installation Qualification (IQ) and…


X-ray fluorescence spectrometry (XRF) enables elemental analysis of a broad range of materials, including liquids, solids, and loose powders. Developed to satisfy the most challenging process control and R&D applications, the Zetium spectrometer leads the market in high-quality design and novel features for sub ppm to percentage analysis of elements across the periodic table including all elements required for elemental impurity analysis.

Zetium is a revolutionary spectrometer based on numerous years of expertise and success with the company's extensive analytical X-ray portfolio. The platform showcases SumXcore technology, which combines EDXRF and WDXRF for the best of both worlds.
Quick Contact PANalytical
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