Drug DiscoveryResearch & Development December 6, 2018 Biopharmaceutical firm UCB to invest £1bn in UK for research and development By PBR Staff Writer UCB will build a new £150mto £200m research and development facility as part of the total investment over the next five years. The transition to the facility will
Clinical TrialsHuman Trials December 5, 2018 J&J’s Darzalex reduces disease progression in multiple myeloma study By PBR Staff Writer The phase 3 MAIA study showed that the daratumumab, in combination with lenalidomide and dexamethasone (Rd), has reduced the risk of disease progression or death in patients with
Drug DiscoveryResearch & Development December 4, 2018 DeepMind’s AlphaFold uses AI technology to predict protein shapes By PBR Staff Writer DeepMind further claimed that its AI-driven system, AlphaFold, is capable of generating 3D models of proteins that are highly accurate and potentially capable of solving one of the
Drug DiscoveryPre-clinical Studies December 3, 2018 Redx expects to start first-in-man studies with RXC006 during 2020 By PBR Staff Writer RXC006 is being developed as an orally administered and first-in-class treatment for the orphan disease idiopathic pulmonary fibrosis (IPF), which is a chronic lung condition. RXC006, which is
Drug DiscoveryPre-clinical Studies November 29, 2018 Cyxone MS drug T20K succeeds in preclinical program By PBR Staff Writer According to Cyxone, T20K during the preclinical program has been shown to be safe for people to ingest. The Swedish clinical biotech company, which has concluded the preclinical
Clinical TrialsHuman Trials November 28, 2018 Vedanta Biosciences starts phase 1 study of VE202 to treat IBD By PBR Staff Writer Janssen Research & Development is undertaking the study. Vedanta Biosciences had granted the licensing rights of VE202 in 2015 to Janssen Biotech. The microbiome-derived product candidate is being
Clinical TrialsHuman Trials November 27, 2018 BMS’ Opdivo plus Yervoy fails to improve OS in lung cancer study By PBR Staff Writer The trial has not achieved its primary endpoint of OS with Opdivo (nivolumab) 1mg/kg in combination with Yervoy (ipilimumab) 3mg/kg against placebo as a maintenance therapy for patients
RegulationApprovals November 26, 2018 Mundipharma’s Neulasta biosimilar Pelmeg secures approval in Europe By PBR Staff Writer The approval of Pelmegis follows the recommendation of the Medicinal Products for Human Use (CHMP), which was based on regulatory submission of significant biosimilarity data from analytical, biofunctional
Production & SalesLaunches November 23, 2018 GSK, Kyowa Hakko Kirin to commercialize anemia drug daprodustat in Japan By PBR Staff Writer Daprodustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, which is under phase 3 development by GSK to treat anemia associated with chronic kidney disease (CKD). Inhibition of
RegulationApprovals November 22, 2018 Pfizer’s Daurismo gets FDA approval to treat elderly adults with AML By PBR Staff Writer Daurismo is claimed to be the first and only FDA-approved Hedgehog pathway inhibitor for AML. Daurismo, which is taken in combination with low-dose cytarabine (LDAC), has not been