Drug DiscoveryResearch & Development August 12, 2020 Bayer to buy UK biotech company KaNDy Therapeutics By PBR Staff Writer The acquisition of KaNDy Therapeutics will allow Bayer to expand its drug development pipeline in women’s healthcare. The deal also allows KaNDy Therapeutics to secure potential milestone payments
Drug DiscoveryResearch & Development August 11, 2020 Ligand Pharmaceuticals to buy Pfenex for up to $516m By PBR Staff Writer Under the deal, Ligand Pharmaceuticals will purchase all outstanding shares of Pfenex for $12 per share in cash or $438m in equity value on a fully diluted basis.
Production & SalesManufacturing August 10, 2020 Takeda to license Novavax’ Covid-19 vaccine candidate NVX‑CoV2373 By PBR Staff Writer The deal between the firms allows Takeda Pharmaceutical to undertake the local production and commercialisation of NVX‑CoV2373 in Japan, which will be backed by funding from the Japanese
RegulationApprovals August 10, 2020 Roche gets FDA nod for Evrysdi to treat spinal muscular atrophy By PBR Staff Writer Evrysdi is a survival of motor neuron 2 (SMN2) splicing modifier created for the treatment of SMA caused by mutations in chromosome 5q, which lead to SMN protein
RegulationApprovals August 7, 2020 ViiV Healthcare gets FDA expanded approval for HIV-1 drug Dovato By PBR Staff Writer The approval will enable ViiV Healthcare to use the complete regimen as a replacement for the current antiretroviral (ARV) regimen in adults who are virologically suppressed on a
RegulationApprovals August 6, 2020 GSK secures FDA nod for BLENREP to treat relapsed or refractory multiple myeloma By PBR Staff Writer BLENREP has been approved as a monotherapy treatment for adult patients with relapsed or refractory multiple myeloma who have secured at least four prior therapies including an anti-CD38
RegulationApprovals August 5, 2020 ReViral secures FDA fast track status for sisunatovir to treat severe RSV infection By PBR Staff Writer Sisunatovir is an orally administered fusion inhibitor designed to inhibit RSV replication by suppressing RSV F-mediated fusion of RSV with the host cell. RSV is a respiratory pathogen
RegulationApprovals July 31, 2020 Takeda gets FDA breakthrough therapy status for pevonedistat to treat higher-risk HR-MDS By PBR Staff Writer MDS is a rare form of bone marrow-related cancer, which will be resulted due to irregular blood cell production within the bone marrow. Pevonedistat, a first-in-class NEDD8-activating enzyme
Clinical TrialsHuman Trials July 30, 2020 Roche’s tocilizumab fails to achieve primary endpoints for Covid-19-related pneumonia By PBR Staff Writer The phase III COVACTA study of tocilizumab did not reach its primary endpoint of improved clinical status in hospitalised adult patients with severe Covid-19 associated pneumonia. Roche’s trial
Production & SalesManufacturing July 29, 2020 DFC grants $765m loan to Kodak to establish new pharma business unit By PBR Staff Writer The US technology company signed a letter of interest (LOI) with the DFC to secure a loan to establish Kodak Pharmaceuticals, a new business unit that will engage