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news.A preclinical trial conducted by Cytori Therapeutics has yielded results that support therapeutic opportunities for adult stem and regenerative cells derived from fat tissue in the treatment of cardiac injury following heart attack.
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Cytori, in collaboration with researchers from the University of California in Los Angeles, has illustrated that adipose (fat) derived stem and regenerative cells can improve left ventricular function after an acute myocardial infarction (heart attack).
In the study, rats were injected in the left ventricle with either adipose-derived stem and regenerative cells or saline solution following heart attack. After 12 weeks, rats treated with adipose derived stem and regenerative cells demonstrated significant improvements in commonly accepted measures of heart function including contractility, ejection fraction (pumping of blood), tissue damage and other measures.
“These findings, combined with our additional data, confirm the broad therapeutic opportunities for adipose stem and regenerative cells in multiple disease areas, including cardiovascular injury,” stated Christopher Calhoun, CEO of Cytori Therapeutics. “The ability of these stem cells to contribute to the repair of multiple tissue types is particularly important given that adipose tissue is the most abundant known source of adult stem cells.”